Maria Felice Brizzi Selected Research

Interleukin-3 (Interleukin 3)

10/2020	Targeting IL-3Rα on tumor-derived endothelial cells blunts metastatic spread of triple-negative breast cancer via extracellular vesicle reprogramming.
1/2018	IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle (EV)-mediated vessel formation by targeting the β-catenin pathway.
7/2008	Interleukin-3 promotes expansion of hemopoietic-derived CD45+ angiogenic cells and their arterial commitment via STAT5 activation.
9/2005	The interaction between KDR and interleukin-3 receptor (IL-3R) beta common modulates tumor neovascularization.
3/2004	IL-3 affects endothelial cell-mediated smooth muscle cell recruitment by increasing TGF beta activity: potential role in tumor vessel stabilization.
7/2002	HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells.

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Maria Felice Brizzi Research Topics

Disease

17	Neoplasms (Cancer) 01/2022 - 03/2004
5	Breast Neoplasms (Breast Cancer) 04/2017 - 01/2014
4	Fibrosis (Cirrhosis) 10/2021 - 01/2018
4	Inflammation (Inflammations) 01/2020 - 08/2012
4	Type 2 Diabetes Mellitus (MODY) 01/2019 - 04/2010
3	Ischemia 12/2020 - 01/2017
2	Acute Coronary Syndrome 09/2021 - 01/2021
2	Pathologic Processes 10/2020 - 11/2016
2	Neoplasm Metastasis (Metastasis) 10/2020 - 04/2017
2	Diabetic Nephropathies (Diabetic Nephropathy) 01/2019 - 08/2004
2	Diabetes Complications 04/2015 - 01/2015
1	Reperfusion Injury 09/2021
1	Infections 09/2021
1	Sepsis (Septicemia) 09/2021
1	Thrombotic Microangiopathies 04/2021
1	Vasculitis (Vasculitides) 04/2021
1	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 04/2021
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 04/2021
1	Ulcer 04/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Triple Negative Breast Neoplasms 10/2020
1	Weight Loss (Weight Reduction) 01/2020
1	Necrosis 01/2020
1	Cicatrix (Scar) 10/2019
1	Hepatocellular Carcinoma (Hepatoma) 06/2019
1	Hyperglycemia 01/2019
1	Disease Progression 12/2018
1	Lymphoma (Lymphomas) 12/2018
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2018
1	Ovarian Neoplasms (Ovarian Cancer) 01/2018
1	Infarction (Infarctions) 12/2017
1	Heart Failure 12/2017
1	Heart Diseases (Heart Disease) 12/2017
1	Hypertension (High Blood Pressure) 09/2017
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2017
1	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2017
1	Shock 01/2017
1	Liver Diseases (Liver Disease) 01/2017
1	Wounds and Injuries (Trauma) 11/2016
1	Melanoma (Melanoma, Malignant) 01/2016
1	Glucose Intolerance 04/2015
1	Peripheral Arterial Disease 04/2015
1	Carcinoma (Carcinomatosis) 01/2014

Drug/Important Bio-Agent (IBA)

6	Interleukin-3 (Interleukin 3)IBA 10/2020 - 07/2002
6	MicroRNAs (MicroRNA)IBA 01/2020 - 08/2010
5	GhrelinIBA 12/2017 - 04/2010
4	CateninsIBA 10/2021 - 01/2018
4	Biomarkers (Surrogate Marker)IBA 12/2018 - 04/2013
4	Proteins (Proteins, Gene)FDA Link 01/2017 - 07/2002
3	IntegrinsIBA 04/2017 - 08/2007
3	erucylphosphocholineIBA 04/2010 - 05/2007
2	salicylhydroxamic acid (SHAM)IBA 09/2021 - 01/2021
2	Lipid Bilayers (Lipid Bilayer)IBA 08/2021 - 06/2021
2	Therapeutic UsesIBA 04/2021 - 01/2019
2	Biological ProductsIBA 12/2020 - 11/2016
2	aristolochic acid I (aristolochic acid)IBA 01/2020 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 08/2012
2	Streptozocin (Streptozotocin)FDA Link 01/2019 - 01/2019
2	CytokinesIBA 01/2018 - 02/2005
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2017 - 04/2015
2	Stem Cell FactorIBA 01/2014 - 01/2014
1	Metformin (Glucophage)FDA LinkGeneric 09/2021
1	Insulin (Novolin)FDA Link 09/2021
1	ThiazolidinedionesIBA 09/2021
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 04/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	VimentinIBA 10/2020
1	Pharmaceutical PreparationsIBA 10/2020
1	CreatinineIBA 01/2020
1	Urea (Carbamide)FDA LinkGeneric 01/2020
1	Neuregulin-1 (Neuregulin 1)IBA 01/2020
1	NitrogenIBA 01/2020
1	ResveratrolIBA 01/2019
1	Sirtuin 1IBA 01/2019
1	Complement System Proteins (Complement)IBA 12/2018
1	Glycogen Synthase (Synthase I)IBA 01/2018
1	Adenosine Triphosphate (ATP)IBA 12/2017
1	Adrenergic Agents (Adrenergic Drugs)IBA 12/2017
1	mitochondrial K(ATP) channelIBA 12/2017
1	Peptides (Polypeptides)IBA 12/2017
1	Endothelin-1 (Endothelin 1)IBA 12/2017
1	PotassiumIBA 12/2017
1	AntioxidantsIBA 09/2017
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2017
1	Focal Adhesion Protein-Tyrosine KinasesIBA 04/2017
1	Activated-Leukocyte Cell Adhesion Molecule (Neurolin)IBA 01/2016
1	ChromatinIBA 01/2015
1	VaccinesIBA 01/2014
1	theasinensin AIBA 01/2014
1	DNA (Deoxyribonucleic Acid)IBA 01/2014
1	ADAM17 ProteinIBA 01/2014
1	Conditioned Culture MediaIBA 01/2014
1	Laminin ReceptorsIBA 01/2014

Therapy/Procedure

5	Therapeutics 01/2022 - 12/2013
2	Percutaneous Coronary Intervention 09/2021 - 01/2021
1	Glycemic Control 09/2021
1	Intravenous Injections 10/2020
1	Liver Transplantation 01/2017
1	Hepatectomy 01/2017
1	Drug Therapy (Chemotherapy) 01/2014